李 刚

 职称: 教授     学历: 博士                 所属部门: 植物生理学系

 招生专业: 生物学/植物生理方向（博士、硕士） 生物技术与工程（专硕）

E-mail: gangli@sdau.edu.cn

个人简介

 李刚，博士、教授、博士生导师。先后入选教育部“长江学者奖励计划”特聘教授、国家海外高层次人才引进计划（青年项目）、山东省泰山学者海外特聘专家、并获得山东省杰出青年基金资助。2001年毕业于山东师范大学，获学士学位。2006年毕业于中科院上海生命科学研究院植物生理生态研究所，获博士学位。2007年至2011年间，先后在美国康奈尔大学园艺学院、布思汤普森植物研究所（BTI）及耶鲁大学进行博士后研究。2011年8月起受聘于山东农业大学生命科学学院。

 近年来，主持国家自然科学基金项目6项，以及科技部重点基础研究发展计划（青年973计划）子课题1项。以第一作者或通讯作者在《Nature Cell Biology》《Trends in Plant Science》《Molecular Plant》《The Plant Cell》《Plant Biotechnology Journal》《Plant Physiology》《Journal of Integrative Plant Biology》等国际权威学术期刊发表论文30余篇；累计发表学术文章50余篇，总引用次数超过2600次。研究成果获得国内外同行的广泛认可与高度关注。

个人荣誉

 教育部长江学者特聘教授

 中组部青年千人

 山东省泰山学者海外特聘专家

教学工作

 承担本科生《植物生理学》以及研究生《高级植物生理学》、《植物生理实验技术》等课程的教学工作，所在教学团队荣获省级教学团队称号。

研究方向

  光是调控植物生长发育的关键环境因子，不仅为光合作用提供能量来源，同时作为重要环境信号，直接参与调控植物生命周期中的多个生理过程。在密植条件下，植物叶片相互遮蔽导致冠层内部光环境劣化，光照强度降低、红光/远红光比值（R:FR）显著下降，进而诱发植物产生避荫反应。主要表现为株高与穗位高增加、叶夹角减小、茎秆机械强度下降，最终引发倒伏、空秆、秃尖等不利性状，严重消弱密植增产潜力，成为制约作物密植高产的关键瓶颈。因此，系统解析植物避荫反应的分子机理，是突破密植障碍、培育耐密高产新品种的重要理论基础，对保障国家粮食安全、推动农业可持续发展具有重要战略意义。

本研究团队聚焦光信号调控植物生长发育的分子机制解析及应用，主要围绕以下两个方向开展研究：

    1. 植物光信号转导的分子机制研究：以模式植物拟南芥为材料，结合运用正向与反向遗传学、生物化学等多种方法，筛选并鉴定光信号转导途径的关键因子，系统揭示其在植物生长发育及逆境胁迫响应中的生物学功能与分子机制。

    2. 作物耐密高产的分子机理研究：以玉米、小麦等主要农作物为研究对象，运用单细胞、空间转录组等先进技术，并结合群体遗传学和细胞学等方法，致力于克隆调控耐密株型建成及密植遮荫反应的关键基因，解析其上下游调控网络，阐明作物对密植环境的分子响应机制，为作物耐密高产育种提供理论支撑与基因资源。

科研项目

1. 国家自然科学基金委员会，面上项目，光受体phyB与LDS1互作协同调控叶片和气孔运动的机理研究，32570296，2026.01至2029.12, 主持

2. 国家自然科学基金委员会，面上项目，玉米phyB与LG1互作协同调控避荫反应的分子机理研究，32270263, 2023.01至2026.12，主持

3. 国家自然科学基金委员会，重大研究计划-集成项目，玉米株型建成调控网络研究，92035302, 2021.01至2021.12，子课题主持

4. 国家自然科学基金委员会，面上项目，光信号蛋白FHY3调控叶片衰老的分子机理研究，31870266, 2019.01至2022.12，主持

5. 国家自然科学基金委员会，面上项目，拟南芥光信号蛋白调控淀粉代谢的分子机理研究，31670249, 2017.01至2020.12，主持

6. 国家自然科学基金委员会，面上项目，光信号途径FHY3蛋白表达调控及信号转导分子机理研究，31271309, 2013.01至2016.12，主持

7. 科技部，青年973项目，玉米叶型建成分子机理研究，2014CB147300, 2014.01至2018.08，子课题主持

8. 山东省科技厅，自然科学杰出青年基金，光信号转导途径FHY3蛋白表达调控的分子机理研究，JQ201208, 2012.01至2014.12，主持 

发表论文

1. Tao Q., Wang G., Wang Z., An Y, Ma L., Li G. (2026). Phytochrome B: Diverse roles in plant biology and breeding potential in crops. Plant Commun. Accepted. 通讯作者

2. Shi Q., Wang Q., Wang G., An Y., Yang H., Tao Q., Xia Y., Jiao Z., Li N., Gao R., Li J., Kong F., Zhang H., Li P., Gou M., Wang H., Li B., Li G. (2026). Mechanical strength: an unrecognized target in the genetic improvement of crops. Plant Biotech J. DOI:10.1111/pbi.79627. 通讯作者

3. Ma L., Zhu F., Xu Y., Li N., Xiang M., Shi Q., Li G., and Qin X. (2026). WRKY20 integrates sugar signaling to modulate plant growth and metabolism. Plant Physiol. DOI:10.1093/plphys/kiag085.

4. Li Q., Lai J., Chen J., Li L., Song W., Xin B., Zhao H., Xiao Y., Tian F., Li G., et al. (2025). Decades' progress and prospects on maize functional genomics and molecular breeding. Sci China Life Sci. 68, 3509-3574.

5. Wang X., Jiao Z., Zhang Y., Shi Q., Wang Q., Zhou F., Xu D., Wang G., Kong F., Zhang H., Li P., Wang H., and Li G. (2025). DBB2 regulates plant height and shade avoidance responses in maize. JIPB 67, 1323-1338. 通讯作者

6. Shi Q., Xia Y., Xue N., Wang Q., Tao Q., Li M., Xu D., Wang X., Kong F., Zhang H., and Li G. (2024). Modulation of starch synthesis in Arabidopsis via phytochrome B-mediated light signal transduction. JIPB 66, 973-985. 通讯作者

7. Shi Q., Xia Y., Wang Q., Lv K., Yang H., Cui L., Sun Y., Wang X., Tao Q., Song X., Xu D., Xu W., Wang X., Wang X., Kong F., Zhang H., Li B., Li P., Wang H., and Li G. (2024). Phytochrome B interacts with LIGULELESS1 to control plant architecture and density tolerance in maize. Mol Plant 17, 1255-1271. 通讯作者

8. Wang Q., Guo Q., Shi Q., Yang H., Liu M., Niu Y., Quan S., Xu D., Chen X., Li L., Xu W., Kong F., Zhang H., Li P., Li B., and Li G. (2024). Histological and single-nucleus transcriptome analyses reveal the specialized functions of ligular sclerenchyma cells and key regulators of leaf angle in maize. Mol Plant 17, 920-934. 通讯作者

9. Song X., Guo P., Xia K., Wang M., Liu, Y., Chen L., Zhang J., Xu M., Liu N., Yue Z., Li G., Liu M., Fang L., Deng XW., and Li B. (2023). Spatial transcriptomics reveals light-induced chlorenchyma cells involved in promoting shoot regeneration in tomato callus. PNAS 120: e2310163120.

10. Wang Q., Liu M., Quan S., Shi Q., Tian T., Zhang H., Wang H., and Li G. (2023). FAR-RED ELONGATED HYPOCOTYL3 increases leaf longevity by delaying senescence in Arabidopsis. Plant Cell Environ. 46, 1582-1595. 通讯作者

11. Chen Q., Zhang J., and Li G. (2022). Dynamic epigenetic modifications in plant sugar signal transduction. Trends Plant Sci. 27, 379-390. 通讯作者

12. Wang X., Wang X., Sun S., Tu X., Lin K., Qin L., Wang X., Li G., Zhong S., and Li P. (2022). Characterization of regulatory modules controlling leaf angle in maize. Plant Physiol. 190, 500-515.

13. Dai X., Tu X., Du B., Dong P., Sun S., Wang X., Sun J., Li G., Lu T., Zhong S., and Li P. (2022). Chromatin and regulatory differentiation between bundle sheath and mesophyll cells in maize. Plant J. 109, 675-692

14. Han Z., Yang T., Guo Y., Cui WH., Yao LJ., Li G., Wu AM., Li JH., and Liu LJ. (2021). The transcription factor PagLBD3 contributes to the regulation of secondary growth in Populus. J Exp Bot. 72, 7092-7106.

15. Zhao H., Xu D., Tian T., Kong F., Lin K., Gan S., Zhang H., and Li G. (2021). Molecular and functional dissection of EARLY-FLOWERING 3 (ELF3) and ELF4 in Arabidopsis. Plant Sci. 303, 110786. 通讯作者

16. Ma L., and Li G. (2021). Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 negatively regulates carbon starvation responses. Plant Cell Environ. 44, 1816-1829. 通讯作者

17. Tian T., Ma L., Liu Y., Xu D., Chen Q., and Li G. (2020). Arabidopsis FAR-RED ELONGATED HYPOCOTYL3 integrates age and light signals to negatively regulate leaf senescence. Plant Cell 32, 1574-1588. 通讯作者

18. Liu Y., Ma M., Li G., Yuan L., Xie Y., Wei H., Ma X., Li Q., Devlin PF., Xu X., and Wang H. (2020). Transcription factors FHY3 and FAR1 regulate light-induced CIRCADIAN CLOCK ASSOCIATED1 gene expression in Arabidopsis. Plant Cell 32, 1464-1478.

19. Zhang X., Liu L., Wang H., Gu Z., Liu Y., Wang M., Wang M., Xu Y., Shi Q., Li G., Tong J.,Xiao L., Wang ZY., Mysore KS., Wen J., Zhou C. (2020). MtPIN1 and MtPIN3 play dual roles in regulation of shade avoidance response under different environments in Medicago truncatula. Int J Mol Sci. 21, 8742.

20. Zhao H., Lin K., Ma L., Chen Q., Gan S., and Li G. (2020). Arabidopsis nuclear factor Y A8 inhibits the juvenile-to-adult transition by activating transcription of MIR156s. J Exp Bot. 71, 4890-4902. 通讯作者

21. Xu D., Wu D., Li XH., Jiang Y., Tian T., Chen Q., Ma L., Wang H., Deng XW., and Li G. (2020). Light and abscisic acid coordinately regulate greening of seedlings. Plant Physiol. 183, 1281-1294. 通讯作者

22. Ma L., Li Y., Li X., Xu D., Lin X., Liu M., Li G., and Qin X. (2019). FAR-RED ELONGATED HYPOCOTYLS3 negatively regulates shade avoidance responses in Arabidopsis. Plant Cell Environ. 42, 3280-3292. 通讯作者

23. Lin K., Zhao H., Gan S., and Li G. (2019). Arabidopsis ELF4-like proteins EFL1 and EFL3 influence flowering time. Gene 700, 131-138. 通讯作者

24. Shi Q., Kong F., Zhang H., Jiang Y., Heng S., Liang R., Ma L., Liu J., Lu X., Li P., and Li G. (2019). Molecular mechanisms governing shade responses in maize. BBRC 516, 112-119. 通讯作者

25. Ma L., and Li G. (2019). Auxin-dependent cell elongation during the shade avoidance response. Front Plant Sci. 10, 914. 通讯作者

26. Chen Q., Xu X., Xu D., Zhang H., Zhang C., and Li G. (2019). WRKY18 and WRKY53 coordinate with HISTONE ACETYLTRANSFERASE1 to regulate rapid responses to sugar. Plant Physiol. 180, 2212-2226. 通讯作者

27. Zhang T., Lv W., Zhang H., Ma L., Li P., Ge L., and Li G. (2018). Genome-wide analysis of the basic Helix-Loop-Helix (bHLH) transcription factor family in maize. BMC Plant Biol. 18, 235. 通讯作者

28. Ma L., and Li G. (2018). FAR1-related sequence (FRS) and FRS-related factor (FRF) family proteins in Arabidopsis growth and development. Front Plant Sci. 9, 692. 通讯作者

29. Zhang QQ., Li Y., Fu ZY., Liu XB., Yuan K., Fang Y., Liu Y., Li G., Zhang XS., Chong K., and Ge L. (2018). Intact Arabidopsis RPB1 functions in stem cell niches maintenance and cell cycling control. Plant J. 95, 150-167.  

30. Li J., Wang Y., Yu B., Song Q., Liu Y., Chen THH., Li G., and Yang X. (2018). Ectopic expression of StCBF1and ScCBF1 have different functions in response to freezing and drought stresses in Arabidopsis. Plant Sci. 270, 221-233.

31. Kong F., Zhang T., Liu J., Heng S., Shi Q., Zhang H., Wang Z., Ge L., Li P., Lu X., and Li G. (2017). Regulation of leaf angle by auricle development in Maize. Mol Plant 10, 516-519. 通讯作者

32. Shi Q., Zhang H., Song X., Jiang Y., Liang R., and Li G. (2017). Functional characterization of the maize phytochrome-interacting factors PIF4 and PIF5. Front Plant Sci. 8, 2273. 通讯作者

33. Ma L., Xue N., Fu X., Zhang H., and Li G. (2017). Arabidopsis thaliana FAR-RED ELONGATED HYPOCOTYLS3 (FHY3) and FAR-RED-IMPAIRED RESPONSE1 (FAR1) modulate starch synthesis in response to light and sugar. New Phytol. 213, 1682-1696. 通讯作者

34. Zhao H., Wu D., Kong F., Lin K., Zhang H., and Li G. (2017). The Arabidopsis thaliana nuclear factor Y transcription factors. Front Plant Sci. 10, 7, 2045. 通讯作者

35. Ma L., Tian T., Lin R., Deng XW., Wang H., and Li G. (2016). Arabidopsis FHY3 and FAR1 regulate light-induced myo-inositol biosynthesis and oxidative stress responses by transcriptional activation of MIPS1. Mol Plant 9, 541-557. 通讯作者

36. Dou H., Xv K., Meng Q., Li G., and Yang X. (2015). Potato plants ectopically expressing Arabidopsis thaliana CBF3 exhibit enhanced tolerance to high-temperature stress. Plant Cell Environ. 38, 61-72.

37. Wang B., Ma M., Lu H., Meng Q., Li G., and Yang X. (2015). Photosynthesis, sucrose metabolism, and starch accumulation in two NILs of winter wheat. Photosynth Res. 126, 363-373.

38. Chen F., Li B., Li, G., Charron, JB., Dai, M., Shi, X., and Deng, XW. (2014). Arabidopsis phytochrome A directly targets numerous promoters for individualized modulation of genes in a wide range of pathways. Plant Cell 26, 1949-1966.

39. Li M., Guo S., Xu Y., Meng Q., Li G., and Yang X. (2014). Glycine betaine-mediated potentiation of HSP gene expression involves calcium signaling pathways in tobacco exposed to NaCl stress. Physiol Plant 150, 63-75.

40. Li M., Li Z., Li S., Guo S., Meng Q., Li G., and Yang X. (2014). Genetic engineering of glycine betaine biosynthesis reduces heat-enhanced photoinhibition by enhancing antioxidative defense and alleviating lipid peroxidation in Tomato. Plant Mol Biol Rep. 32, 42-51.

41. Huang X., Ouyang X., Yang P., Lau OS., Li G., Li J., Chen H., and Deng XW. (2012). Arabidopsis FHY3 and HY5 positively mediate induction of COP1 transcription in response to photomorphogenic UV-B light. Plant Cell 24, 4590-4606.

42. Dai M., Zhang C., Kania U., Chen F., Xue Q., McCray T., Li G., Qin G., Wakeley M., Terzaghi W., Wan J., Zhao Y., Xu J., Friml J., Deng XW., Wang H. (2012). A PP6-type phosphatase holoenzyme directly regulates PIN phosphorylation and auxin efflux in Arabidopsis. Plant Cell 24, 2497-2514.

43. Chen F., Shi X., Chen L., Dai M., Zhou Z., Shen Y., Li J., Li G., Wei N., and Deng XW. (2012). Phosphorylation of FAR-RED ELONGATED HYPOCOTYL1 is a key mechanism defining signaling dynamics of phytochrome A under red and far-red light in Arabidopsis. Plant Cell 24, 1907-1920.

44. Lin Q., Wang D., Dong H., Gu S., Cheng Z., Gong J., Qin R., Jiang L., Li G., Wang JL., Wu F., Guo X., Zhang X., Lei C., Wang H., Wan J. (2012). Rice APC/C(TE) controls tillering by mediating the degradation of MONOCULM 1. Nat Commun. 3, 752.

45. Li G., Siddiqui H., Teng Y., Lin R., Wan XY., Li J., Lau OS., Ouyang X., Dai M., Wan J., Devlin PF., Deng XW., Wang H. (2011). Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis. Nat Cell Biol. 13, 616-622. 第一作者

46. Li J., Li G., Wang H., and Deng XW. (2011). Phytochrome signaling mechanisms. Arabidopsis Book 9, e0148.

47. Lau OS., Huang X., Charron JB., Lee JH., Li G., and Deng XW. (2011). Interaction of Arabidopsis DET1 with CCA1 and LHY in mediating transcriptional repression in the plant circadian clock. Mol Cell 43, 703-712.

48. Ouyang X., Li J., Li G., Li B., Chen B., Shen H., Huang X., Mo X., Wan X., Lin R., Li S., Wang H., Deng XW. (2011). Genome-wide binding site analysis of FAR-RED ELONGATED HYPOCOTYL3 reveals its novel function in Arabidopsis development. Plant Cell 23, 2514-2535. 并列第一作者

49. Li J., Li G., Gao S., Martinez C., He G., Zhou Z., Huang X., Lee JH., Zhang H., Shen Y., Wang H., Deng XW. (2010). Arabidopsis transcription factor ELONGATED HYPOCOTYL5 plays a role in the feedback regulation of phytochrome A signaling. Plant Cell 22, 3634-3649.

50. Yang H., Liu H., Li G., Feng J., Qin H., Liu X., Xue H., and Wang D. (2009). Reduction of root flavonoid level and its potential involvement in lateral root emergence in Arabidopsis thaliana grown under low phosphate supply. Funct Plant Biol. 36, 564-573.

51. Li G., and Xue HW. (2007). Arabidopsis PLDzeta2 regulates vesicle trafficking and is required for auxin response. Plant Cell 19, 281-295. 第一作者

52. Li G., Lin F., and Xue HW. (2007). Genome-wide analysis of the phospholipase D family in Oryza sativa and functional characterization of PLD beta 1 in seed germination. Cell Res. 17, 881-894. 第一作者

53. Mancuso S., Marras AM., Mugnai S., Schlicht M., Zársky V., Li G., Song L., Xue HW., and Baluska F. (2007). Phospholipase Dzeta2 drives vesicular secretion of auxin for its polar cell-cell transport in the transition zone of the root apex. Plant Signal Behav. 2, 240-244.

54. Xue H., Chen X., and Li G. (2007). Involvement of phospholipid signaling in plant growth and hormone effects. Curr Opin Plant Biol. 10, 483-489.