杨国栋

学历  博士  职称   教授

所属部门    生物化学与分子生物学

招生专业    生物化学与分子生物学、生物技术与工程

（硕士、博士、博后）

联系方式    Email：gdyang@sdau.edu.cn

个人简介

杨国栋，博士，教授，博士研究生导师，泰山学者团队学术骨干。 2012年6月获得山东农业大学生物化学与分子生物学博士学位。2013至2016年，美国加州大学河滨分校植物科学系访问学者。承担了本科生《生物化学A（双语）》、《生物化学实验》以及研究生《高级生化实验技术》等课程的教学工作。近年来，主要主持了国家自然科学基金面上项目、山东省良种工程、山东省自然科学基金面上项目。并参加了国家高技术研究发展计划(863计划)、国家重点基础研究发展计划（973计划）等多项课题。获得了基因发明专利两项。相关科研成果发表在《Nature Communications》《Trends in Plant Science》、《Journal of Integrative Plant Science》、《Molecular Plant》、《Molecular Cell》等著名学术刊物。

教学工作

生物化学与分子生物学国家级教学团队骨干成员，生物化学国家级双语教学示范课程主讲教师。承担本科生《生物化学A（双语）》和《生物化学实验》，研究生《高级生化实验技术》等课程的教学工作。

研究方向

本课题组前期研究发现，ABA信号通路的核心组分SnRK2，其亚细胞定位，随ABA/胁迫处理时间的延长，由经典报道的细胞核定位，逐渐转移至过氧化物酶体膜。过氧化物酶体是细胞代谢的中心（特别是在胁迫条件下）。本课题组的研究方向聚焦过氧化物酶体定位的SnRK2，围绕其翻译后水平修饰、过氧化物酶体动态变化等，拟阐明由其介导植物长期适应高盐、干旱等非生物胁迫的分子机理，并应用于小麦抗逆育种。

主要科研项目

2025-2028国家自然科学基金面上项目 32470338  主持

2022-2024  山东省自然科学基金面上项目 ZR2021MC012  主持

2017-2020  山东省良种工程项目 2017LZN025  主持

2015-2018  国家自然科学基金面上项目  31471425   主持

科研奖励

“植物应答温度和高盐胁迫基因的挖掘和调控机制研究”，山东省科学技术奖 二等奖，2016年1月。

其它奖励

获得“山东农业大学2021年研究生‘十佳’研究生导学团队”荣誉称号。

近期代表性论文

Liu Lin, Shu Yafei, Wang Yue, Liu Mingyue, Xu Shuxin, Lu Xiaofan, Zhang Yu, Yu Luyao, Tao Ze, Wang Jiale, Ge Bingkun, Cui Pengzhen, Wu Changai, Huang Jinguang, Yan Kang, Zheng Chengchao, Yang Guodong*, Tian Xin* and Zhang Shizhong*. The pan genome analysis of WOX gene family in apple and the two sides of MdWUS-1 in promoting leaf-borne shoot. Horticulture Research, 2025, 12(8): uhaf117. (影响因子8.7) https://doi.org/10.1093/hr/uhaf117

Li Xiaohu, Wang Meng, Xu Yiran, Guo Qianhuan, Liu Peng, Wu Changai, Yang Guodong, Huang Jinguang, Zhang Shizhong*, Zheng Chengchao* and Yan Kang* (2025). "SRAS1.1 E3 ligase mediates DSK2A degradation to regulate autophagy and drought tolerance in Arabidopsis. EMBO Reports, 2025. (影响因子6.2) https://doi.org/10.1038/s44319-025-00556-9

Liu Xiaoxiao#, Zhang Lei#, Zhao Zeqi, Zheng Yue, Ren Yue, Zhao Xiaomin, Zhang Shizhong, Yang Guodong, Huang Jinguang, Yan Kang, Li Chunlong*, Zheng Chengchao* and Wu Changai*. Regulation of the non-selective Na⁽⁺⁾ importer capacity of NRT1.2/NPF4.6/AIT1 by SOS2-mediated phosphorylation in Arabidopsis. Cell Reports, 2025, 44(6): 115729. (影响因子6.9) https://doi.org/10.1016/j.celrep.2025.115729

Lu Junyao, Li Ning, Li Gaojian, Tian Ziang, Shi Lianping, Wang Yan, Cai Yingao, Zhang Kaiyuan, Sun Wanting, Wang Danyang, Lin Jinxin, Huang Jinguang, Wu Changai, Yan Kang, Zhang Shizhong, Zheng Chengchao* and Yang Guodong*. N-glycosylation of SnRK2s affects NADPH maintenance in peroxisomes during prolonged ABA signalling. Nature Communications, 2024, 15(1): 6630. (影响因子15.7，五年影响因子17.2) https://doi.org/10.1038/s41467-024-50720-3

Highlighted by 2 Spotlight papers in Trends in Plant Science:

Doi: 10.1016/j.tplants.2024.11.015; DOI: 10.1016/j.tplants.2025.03.016.

Liu Lin, Qu Jinghua, Wang Chunyan, Liu Miao, Zhang Chunmeng, Zhang Xinyue, Guo Cheng, Wu Changai, Yang Guodong, Huang Jinguang, Yan Kang, Shu huairui, Zheng Chengchao* and Zhang Shizhong*. An efficient genetic transformation system mediated by Rhizobium rhizogenes in fruit trees based on the transgenic hairy root to shoot conversion. Plant Biotechnology Journal, 2024, 22(8): 2093-2103. (影响因子10.5). Doi: 10.1111/pbi.14328

Wang Jun, Wang Chunyan, Wang Tianrun, Zhang Shizhong, Yan Kang, Yang Guodong, Wu Changai, Zheng Chengchao* and Huang Jinguang. Tyrosylprotein sulfotransferase suppresses ABA signaling via sulfation of SnRK2.2/2.3/2.6. Journal of Integrative Plant Biology, 2023, 65(8): 1846-1851. (影响因子9.3) https://doi.org/10.1111/jipb.13493

Zhang Lei#, Yu Zipeng#, Xu Yang, Yu Miao, Ren Yue, Zhang Shizhong, Yang Guodong, Huang Jinguang, Yan Kang, Zheng Chengchao* and Wu Changai*. Regulation of the stability and ABA import activity of NRT1.2/NPF4.6 by CEPR2-mediated phosphorylation in Arabidopsis. Molecular Plant, 2021, 14(4): 633-646. (影响因子24.1) https://doi.org/10.1016/j.molp.2021.01.009

Lyu, Xiangguang, Cheng Qican, Qin Chao, Li Yinghui, Xu Xinying, Ji Ronghua, Mu Ruolan, Li Hongyu, Zhao Tao, Liu Jun, Zhou Yonggang, Li Haiyan, Yang Guodong, Chen Qingshan and Liu Bin. GmCRY1s modulate gibberellin metabolism to regulate soybean shade avoidance in response to reduced blue light. Molecular Plant, 2021, 14(2): 298-314. (影响因子24.1) https://doi.org/10.1016/j.molp.2020.11.016

Zhai Huawei, Xiong Lu, Li Hongyu, Lyu Xiangguang, Yang Guodong, Zhao Tao, Liu Jun and Liu Bin. Cryptochrome 1 Inhibits Shoot Branching by Repressing the Self-Activated Transciption Loop of PIF4 in Arabidopsis. Plant Communications, 2020, 1(3): 100042. (影响因子11.6) https://doi.org/10.1016/j.xplc.2020.100042

Yang Guodong, Yu Zipeng, Gao Lei*, Zheng Chengchao*. SnRK2s at the Crossroads of Growth and Stress Responses, Trends in Plant Science, 2019, 24(8): 672-676. (影响因子20.8) https://doi.org/10.1016/j.tplants.2019.05.010

Yang Guodong#, Li Yuanyuan#, Wu Binjing, Zhang Kaiyue, Gao Lei*, ZhengChengchao*. MicroRNAs transcriptionally regulate promoter activity in Arabidopsis thaliana, Journal of Integrative Plant Biology, 2019, 61(11):1128-1133. (影响因子 9.3) DOI: 10.1111/jipb.12775

Guan Peiyan, Wang Jun, Li Hui, Xie Chen, Zhang Shizhong, Wu Changai, Yang Guodong, Yan Kang, Huang Jinguang*, Zheng Chengchao*. SENSITIVE TO SALT1, An Endoplasmic Reticulum-Localized Chaperone, Positively Regulates Salt Resistance, Plant Physiology, 2018, 178(3): 1390-1405. (影响因子6.9) DOI: 10.1104/pp.18.00840

Li Dongming#, Palanca S Ana Marie#, Won Soyoun#, Gao Lei, Feng Ying, Vashisht A Ajay, Liu Li, Zhao Yuanyuan, Liu xigang, Wu Xiuyun, Li Shaofang, Le Brandon, Kim Yunju, Yang Guodong, Li Shengben, Liu Jinyuan, Wohlschlegel A James, Guo Hongwei, Mo Beixin, Chen Xuemei* and Law A Julie*. The MBD7 complex promotes expression of methylated transgenes without significantly altering their methylation status, eLife, 2017, 6. DOI: 10.7554/eLife.19893.001

Yan Kang, Liu Peng, Wu Changai, Yang Guodong, Xu Rui, Guo Qianhuan, Huang Jinguang, Zheng Chengchao*. Stress-Induced Alternative Splicing Provides a Mechanism for the Regulation of MicroRNA Processing in Arabidopsis thaliana, Molecular Cell, 2012, 48(4): 521-531. (影响因子16.6) http://dx.doi.org/10.1016/j.molcel.2012.08.032

#共同第一作者；*共同通讯作者。