Binghai Du
发布时间： 2018-06-04                 浏览次数： 37



Binghai Du,Professor, Ph.D.,du_binghai@163.com , 0086-538-8247806

Research Interests:

1.Molecular Biology of Plant Growth Promoting Rhizobacteria

Based on the combination of high-throughput sequencing, genomics, transcriptomics，proteomics，metabolomics，biochemical and molecular biological techniques, Researches focus on the PGPR molecular mechanisms of plant disease biocontrol and plant growth promotion, including functional identification and expression regulation of the genes / gene clusters involved in biosynthesis of NRPSs and singnal molecule in PGPR -Plant interactions and so on.

2. Metabolic Engineering and Synthetic Biology of PGPR

Based on the combination of metabolic engineering, genome engineering and synthetic biology, Researches focus on  genetic modification of Paenibacillus polymyxa SC2, and construction of efficient multi-functional engineering strains for biocontrol, plant growth promotion , activation of soil nutrients and high resistance.  

3. Development of Agricultural Microbial Preparation

On the basis of large scale screening of PGPR , Researches focus on the combination optimization of PGPR strains with different functions such as biocontrol, plant growth promotion, activation of soil nutrients and degradation of plant self toxic substances. The study also includes optimization of culture medium and fermentation process parameters, as well as screening of carrier, dosage form, synergist, protectant, stabilizer and so on. Finally, large-scale production process  of crop-special multi-functional microbial preparation will be established.  

Education:

2004.07-present: Professor, Director of Microbiology, Member of Professor Committee of College of Life Sciences, Director of Microbial Fertilizer Innovation Research Center, Shandong Agricultural University. Deputy Director of the Agricultural Microbiology Specialized Committee of Chinese Society of Microbiology. Member of the Eighth Fertilizer Registration Review Committee of the Ministry of Agriculture, China.

2001.09-2004.06: Ph.D. in Microbiology, China Agricultural University

1993.07-2001.08: Associate Professor, Shandong Agricultural University

1990.09-1993.06: M.Sc. in Microbiology, Institute of Microbiology, Shandong University

1987.07-1990.08: Assistant Professor, Shandong Agricultural University

1983.09-1987.06: B.Sc. in Soil and Agricultural Chemistry, Shandong Agricultural University

Teaching Courses:

1. Agricultural Microbial Technology for undergraduate students 

2. Lectures on Microbiology for master's graduate students  

3. Research Progress on Microbiology for doctoral graduate students

Selected Publications:

  1. Wang C, Li Y, Qiu C, Wang S, Ma J, Shen Y, Zhang Q, Du B, Ding Y and Bao X.2017. Identification of Important Amino Acids in Gal2p for Improving the L-arabinose Transport and Metabolism in Saccharomyces cerevisiae. Front. Microbiol. 8:1391. doi: 10.3389/fmicb.2017.01391

  2. Chengqiang Wang, Jianzhi Zhao, Chenxi Qiu, Shihao Wang, Yu Shen, Binghai Du, Yanqin Ding, and Xiaoming Bao.2017.Coutilization of D-Glucose, D-Xylose, and L-Arabinose in Saccharomyces cerevisiae by Coexpressing the Metabolic Pathways and Evolutionary Engineering. BioMed Res. Int. 8 pages https://doi.org/10.1155/2017/5318232

  3. Di Liu, Qianqian Yang, Ke Ge, Guozhen Qi, Binghai Du, Yanqin Ding. 2017. Promotion of iron nutrition and growth on peanut by Paenibacillus illinoisensis and Bacillus sp. Strains. J Brazil  Microbiol.48(4):656-670

  4. Wang Y, Liu H, Liu K, Wang C, Ma H, Li Y, Hou Q, Liu F, Zhang T, Wang H, Wang B, Ma J, Ge R, Xu B, Yao G, Xu W, Fan L, Ding Y, Du B.2017. Complete genome sequence of Bacillus paralicheniformis MDJK30, a plant growth promoting rhizobacterium with antifungal activity. Genome Announc 5:e00577-17.

  5. Ma J, Liu H, Wang C, Xia Z, Liu K, Hou Q, Li Y, Zhang T, Wang H, Wang B, Wang Y, Ge R, Xu B, Yao G, Jiang Z, Hou W, Ding Y, Du B. 2017. Complete genome sequence of Bacillus subtilis GQJK2, a plant growth-promoting rhizobacterium with antifungal activity.Genome Announc 5:e00467-17. https://doi.org/10.1128/genomeA.00467-17.

  6. Wang B, Liu H, Ma H, Wang C, Liu K, Li Y, Hou Q, Ge R, Zhang T, Liu F, Ma J, Wang Y, Wang H, Xu B, Yao G, Xu W, Fan L, Ding Y, Du B.2017. Complete genome sequence of biocontroller Bacillus velezensis strain JTYP2,isolated from leaves of Echeveria laui. Genome Announc 5:e00505-17. https://doi.org/10.1128/genomeA.00505-17

  7. Liu H, Wang C, Li Y, Liu K, Hou Q, Xu W, Fan L, Zhao J, Gou J, Du B, Ding Y. 2017.

 Complete genome sequence of Paenibacillus polymyxa YC0573, a plant growth–promoting

 rhizobacterium with antimicrobial activity.Genome Announc 5:e01636-16. https://doi.org/10.1128/genomeA.01636-16.

  1. Liu H, Liu K, Li Y, Wang C, Hou Q, Xu W, Fan L, Zhao J, Gou J, Du B, Ding Y. 2017.

 Complete genome sequence of Paenibacillus polymyxa YC0136, a plant growth–promoting

 rhizobacterium isolated from tobacco rhizosphere. Genome Announc 5:e01635-16.

https://doi.org/10.1128/genomeA.01635-16.

  1. Xiaoyang Hou, Xiaoning Yu, Binghai Du, Kai Liu, Liangtong Yao, Sicheng Zhang, Carrie Selin, Dilantha Fernando,Chengqiang Wang, Yanqin Ding. 2016.Single Amino Acid mutation of spo0A results in sporulation deficiency of Paenibacillus polymyxa SC2. Res Microbiol. 167:472-479

  2. Haimeng Guo,Yanan Yang,Kai Liu,Wenfeng Xu,Jianyong Gao,Hairong Duan,Binghai Du,Yanqin Ding,and ChengqiangWang. 2016.Comparative Genomic Analysis of Delftia tsuruhatensis MTQ3 and the Identification of Functional NRPS Genes for Siderophore Production, BioMed Research International. http://dx.doi.org/10.1155/2016/3687619

  3. Qihui Hou, Chengqiang Wang, Xiaoyang Hou, Zhilin Xia, Jiangping Ye, Kai Liu, Hu Liu, Jun Wang, Haimeng Guo,Xiaoning Yu, Yanan Yang, Binghai Du, Yanqin Ding. 2015,Draft Genome Sequence of Brevibacillus brevis DZQ7, a Plant Growth-Promoting Rhizobacterium with Broad-Spectrum Antimicrobial Activity, Genome Announc 3(4):e00831-15 doi:10.1128/genomeA.00831-15.

  4. Qihui Hou, Chengqiang Wang, Haimeng Guo, Zhilin Xia, Jiangping Ye, Kai Liu, Yanan Yang, Xiaoyang Hou, Hu Liu,Jun Wang, Binghai Du, Yanqin Ding. 2015. Draft Genome Sequence of Delftia tsuruhatensis MTQ3, a Strain of Plant Growth-Promoting Rhizobacterium with Antimicrobial Activity, Genome Announc 3(4):e00822-15.doi:10.1128/genomeA. 00822-15.

  5. Shanlin Wang, Wentong Wang, Zhigang Jin, Binghai Du, Yanqin Ding, Ting Ni and Fangzan Jiao. 2013. Screening and diversity of plant growth promoting endophytic bacteria from peanut. African J Microbiol Res. 7(10): 875-884

  6. Mingchao Ma, Zhenya Wang, Li Li, Xin Jiang, Dawei Guan, Fengming Cao, Huijun Chen, Xuan Wang, Delong Shen, Binghai Du, andJun Li. 2012. Complete Genome Sequence of Paenibacillus mucilaginosus 3016, a Bacterium Functional as Microbial Fertilizer. J. Bacteriol. 194(10): 2777–2778

  7. Mingchao Ma, Cuicui Wang, Yanqin Ding, Li Li, Delong Shen, Xin Jiang,Dawei Guan,Fengming Cao, Huijun Chen, Ruihua Feng, Xuan Wang, Yifan Ge, Liangtong Yao, Xiaohui Bing, Xiaohong Yang, Jun Li, and Binghai Du. 2011. Complete Genome Sequence of Paenibacillus polymyxa SC2, a Strain of  Plant Growth Promoting Rhizobacteriium with Broad-Spectrum Antimicrobial Activity. J. Bacteriol. 193(1): 311–312

  8. Yan Zhang, Bing-Hai Du, Zhi-Gang Jin, Zheng-Hua Li, Hong-Ning Song, Yan-Qin Ding. 2011. Analysis of bacterial communities in rhizosphere soil of healthy and diseased cotton (Gossypium sp.) at different plant growth stages. Plant and Soil. 339(1-2):447-455. DOI  

10.1007/s11104-010-0600-2

17. Fengli Jin , Yanqin Ding , Wei Ding , M.S. Reddy, W.G. Dilantha Fernando and Binghai Du. 2011. Genetic Diversity and Phylogeny of Antagonistic Bacteria against Phytophthora nicotianae Isolated from Tobacco Rhizosphere. Int. J. Mol. Sci. 12, 3055-3071

18.Hongning Song, Zhenghua Li, Binghai Du, Guangyi Wang and Yanqin Ding.  2011. Bacterial communities in sediments of the shallow Lake Dongping in China. J Appl Microbiol, DOI: 10.1111/j.1365-2672. 05187.x

19. M. S. Reddy, K. Vijay Krishna Kumar, H.  Sudini, S. Niranjana Raj, S. C. Nayak, S. A. Deepak, G. Chaluvaraju, A. C. U. Shankar, H. S. Shetty, H. S. Prakash, S. R. Niranjana, S. Desai, V. Krishna Rao, K. S. Park, C. M. Ryu, P. Kim, Binghai Du, C. H. Bonfiglio, S. Gnanamanickam and Y. R. Sarma. 2010. PGPR in crop production systems. p.1-2.In M.S.Reddy, S.Desai, J.W.Kloepper(ed.), Plant growth promoting rhizobacteria for sustainable agriculture. Scientific Publishers, Jodhpur, India

20. Fang Tian, Yanqin Ding, Hui Zhu, Liangtong Yao, Binghai Du. 2009. Genetic Diversity of Siderophore-Producing Bacteria of Tobacco Rhizosphere. Brazil J Microbiol. 40:276-284.

21. K. Vijay Krishna Kumar, S. Krishnam Raju, M.S. Reddy, J.W. Kloepper, K.S. Lawrence, D.E. Groth, M.E. Miller, H. Sudini and Binghai Du. 2009. Evaluation of  commercially available PGPR for control ofrice sheath blight caused by Rhizoctonia solani. Journal of Pure and Applied Microbiology. 3(2):485-488